https://archive.md/tj19G
"Long COVID represents the constellation of post-acute and long-term health
effects caused by SARS-CoV-2 infection; it is a complex, multisystem disorder
that can affect nearly every organ system and can be severely disabling. The
cumulative global incidence of long COVID is around 400 million individuals,
which is estimated to have an annual economic impact of approximately $1
trillion—equivalent to about 1% of the global economy. Several mechanistic
pathways are implicated in long COVID, including viral persistence, immune
dysregulation, mitochondrial dysfunction, complement dysregulation, endothelial
inflammation and microbiome dysbiosis. Long COVID can have devastating impacts
on individual lives and, due to its complexity and prevalence, it also has
major ramifications for health systems and economies, even threatening progress
toward achieving the Sustainable Development Goals. Addressing the challenge of
long COVID requires an ambitious and coordinated—but so far absent—global
research and policy response strategy. In this interdisciplinary review, we
provide a synthesis of the state of scientific evidence on long COVID, assess
the impacts of long COVID on human health, health systems, the economy and
global health metrics, and provide a forward-looking research and policy
roadmap."
Via Violet Blue’s
Pandemic Roundup: October 24, 2024
https://www.patreon.com/posts/pandemic-roundup-114604843
Cheers,
*** Xanni ***
--
mailto:xanni@xanadu.net Andrew Pam
http://xanadu.com.au/ Chief Scientist, Xanadu
https://glasswings.com.au/ Partner, Glass Wings
https://sericyb.com.au/ Manager, Serious Cybernetics
