Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

Mon, 4 Dec 2023 04:22:57 +1100

Andrew Pam <xanni [at] glasswings.com.au>

Andrew Pam
<https://www.news-medical.net/news/20231031/Study-reveals-how-SARS-CoV-2-alters-mitochondria-leading-to-energy-outages-and-organ-failure.aspx>

'The lungs were once at the forefront of SARS-Cov-2 research, but as reports of
organ failure and other serious complications poured in, scientists set out to
discover how and why the respiratory virus was causing serious damage to the
body's major organs, including the lungs.

An interdisciplinary COVID-19 International Research Team (COV-IRT), which
includes UNC School of Medicine's Jonathan C. Schisler, PhD, found that
SARS-CoV-2 alters mitochondria on a genetic level, leading to widespread
"energy outages" throughout the body and its major organs. Their findings,
published in Science Translational Medicine, explain how these effects
contribute to long COVID symptoms and point to new therapeutic targets.'

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of
rodent and human hosts
:
https://www.science.org/doi/10.1126/scitranslmed.abq1533

Via Diane A.

Cheers,
       *** Xanni ***
--
mailto:xanni@xanadu.net               Andrew Pam
http://xanadu.com.au/                 Chief Scientist, Xanadu
https://glasswings.com.au/            Partner, Glass Wings
https://sericyb.com.au/               Manager, Serious Cybernetics

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