We’ve been studying the same people for 76 years – this is what we’ve found out about Alzheimer’s disease

Fri, 13 Jan 2023 12:05:23 +1100

Andrew Pam <xanni [at] glasswings.com.au>

Andrew Pam
<https://theconversation.com/weve-been-studying-the-same-people-for-76-years-this-is-what-weve-found-out-about-alzheimers-disease-183949>

"In March 1946, just months after the end of the second world war, James
Douglas began a pioneering and extraordinary study. Based on a representative
sample of 5,362 babies all born in the same week of that month, the study began
as a one-off investigation of the cost of childbirth and the quality and
efficiency of obstetric services. From there it became the longest continuously
running study of health over the human life course in the world.

The Medical Research Council National Survey of Health and Development (NSHD),
also known as the British 1946 birth cohort, continues to this day and the
information enables us to glean new understandings about health – including the
workings of the brain and the development of Alzheimer’s disease. We have been
privileged to continue Douglas’s work and, indeed, today we still use the data
he began gathering over seven decades ago.

In 2016, a sub-study of 502 people from the cohort, known as Insight 46, was
started specifically to address brain ageing and dementia, and their life
course influences. Using cutting-edge imaging and AI technology, we have been
observing their brains ever since."

Cheers,
       *** Xanni ***
--
mailto:xanni@xanadu.net               Andrew Pam
http://xanadu.com.au/                 Chief Scientist, Xanadu
https://glasswings.com.au/            Partner, Glass Wings
https://sericyb.com.au/               Manager, Serious Cybernetics

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